For manufacturing of methyl acetoacetate, there are LONZA in Switzerland and Eastman in US internationally. While in China, there are Nantong Acetic Acid Chemical Co., Ltd., Jiangsu Tiancheng biochemical products Co., Ltd. and Wanglong Science and Technology Co., Ltd., in which, Jiangsu Tiancheng is the largest manufacture of methyl acetoacetate and its production capability is 300 thousand tonnes, taking 40% domestic market shares. Nantong Acetic Acid Chemical has the production capability of 200 thousand tonnes and Ningbo Wanglong has the capability of 120 thousand tonnes.
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In 2014, the production capability of methyl acetoacetate of China was around 740 thousand tonnes and the output reached about 680 thousand tonnes. According to construction plans and under-construction plans of China methyl acetoacetate enterprises, in 2021, the production capability is predicted to break 140 thousand tonnes and the output will reach about 136 thousand tonnes
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